Comparison was made with 55 consecutive patients surveyed in 2005.

Marked improvements in the management of acute stroke patients were noted, particularly time to computerised tomography of brain, aspirin administration and multidisciplinary involvement. Significantly, the average Buparlisib in vivo length of hospital stay was reduced by a mean of 10 days from 29.3 +/- A 28 in 2005 to 19.6 +/- A 20

following the establishment of a stroke unit (p = 0.018).

The stroke unit has greatly improved the care of acute stroke patients. Further areas for improvement are highlighted.”
“Herbal species different from the official bearberry, Arctostaphylos uva-ursi, are sold through conventional markets and also through non-controlled Internet websites, putting consumer safety at risk owing to the lack of quality control. Recently, Arctostaphylos Selleck P5091 pungens has become one of the most used species as a raw material for herbal medicines and dietary supplements in the place of official

bearberry, a plant used for the treatment of various urinary disorders. A fingerprint identification based on an integrated application of different analytical techniques (HPTLC, NMR, HPLC-DAD and LC-ESI-MS) is here described to distinguish A. uva-ursi from A. pungens. The HPTLC and HPLC-DAD fingerprints resulted the simplest methods to differentiate the two species, whereas LC-ESI-MS was more useful to quantify arbutin, the main component of bearberry, and to evaluate its different content in the two species. This multidisciplinary study showed for the first time a specific phytochemical fingerprint of the new species A. pungens.”
“Study Design. An in vitro biomechanical study of halo-vest and odontoid screw fixation of Type II dens fracture.

Objective. The objective were to determine upper cervical spine instability due to simulated

dens fracture and investigate stability provided by the halo-vest and odontoid screw, applied individually and combined.

Summary of Background Data. Previous studies have evaluated CH5424802 supplier posterior fixation techniques for stabilizing dens fracture. No previous biomechanical study has investigated the halo-vest and odontoid screw for stabilizing dens fracture.

Methods. A biofidelic skull-neck-thorax model was used with 5 osteoligamentous whole cervical spine specimens. Three-dimensional flexibility tests were performed on the specimens while intact, following simulated dens fracture, and following application of the halo-vest alone, odontoid screw alone, and halo-vest and screw combined. Average total neutral zone and total ranges of motion at C0/1 and C1/2 were computed for each experimental condition and statistically compared with physiologic motion limits, obtained from the intact flexibility test. Significance was set at P < 0.05 with a trend toward significance at P < 0.1.

Results. Type II dens fracture caused trends toward increased sagittal neutral zone and lateral bending range of motion at C1/2.

01). With other patterns, neurological outcome was likely to be influenced by spinal column injury severity.

Conclusion. Injury patterns based on Allen’s classification well-correlated

with the neurological outcome and recovery rate. This was especially evident distractive flexion cases. Thus, Allen’s classification can be a predictor of neurological outcome after cervical spine AZD0530 injury.”
“The aims of this study were (1) to determine attitudes among the American public regarding foreigners coming to the United States for the purposes of transplantation, and (2) to investigate the impact this practice might have on the public’s willingness to donate organs. A probability-based national sample of adults age >= 18 was asked whether people should be allowed to travel to the United States to receive a transplant, and whether INCB028050 mw this practice would discourage the respondents from becoming an organ donor. Among 1049 participants, 30% (95% CI 25-34%) felt

that people should not be allowed to travel to the United States to receive a deceased donor transplant, whereas 28% felt this would be acceptable in some cases. Thirty-eight percent (95% CI 33-42%) indicated that this practice might prevent them from becoming an organ donor. In conclusion, deceased-donor transplantation of foreigners is opposed by many Americans. Media coverage of this practice has the potential to adversely affect organ donation.”
“Photosynthesis irradiance (P-E)-curves describe the photosynthetic performance of autotrophic organisms. From LY3039478 Stem Cells & Wnt inhibitor these P-E-curves

the photosynthetic parameters alpha-slope, P(max), and E(k) Can be deduced which are often used to characterize and to compare different organisms or organisms in acclimation to different environmental conditions. Particularly, for in situ-measurements of P-E curves of phytoplankton the analysis of variable chlorophyll fluorescence proved its potential as a sensitive and rapid method. By using Chlorella vulgaris (Trebouxiophyceae), Nannochloropsis sauna (Eustigmatophyceae), Skeletonema costatum and Cyclotella meneghiniana (Bacillariophyceae), the present study investigated the influence of cellular bio-optical properties on the correlation of the photosynthetic parameters derived from fluorescence-based P-E-curves with photosynthetic parameters obtained from the measurement of oxygen evolution. It is demonstrated that small planktonic algae show a wide range of cellular absorptivity which was subject to species-specifity, growth stage and environmental conditions, e.g. nutrient limitation. This variability in bio-optical properties resulted in a great deviation of relative electron transport rates (rETRs) from oxygen-based photosynthesis rates.

For group one, we performed a sham operation. The abdomen was dissected, the right kidney was harvested, and then the left renal pedicle exposed. Renal clamping was not applied. For group 2, rats underwent left renal ischemia for 60 minutes followed by reperfusion for 45 minutes. For group 3, the same surgical procedure as in group 2 was performed, and dexmedetomidine (100

g/kg, intraperitoneal) was administrated at the starting time of reperfusion. The rats were sacrificed after reperfusion, and the kidney tissue was harvested. The histopathological score in the kidney of the I-R/dexmedetomidine-treated group rats was significantly lower than that of I-R/untreated group rats. This score in I-R/untreated group rats was higher than the other two groups, which was statistically significant. In the I-R/untreated group rats, kidneys of untreated ischemia

rats showed tubular cell swelling, cellular VE-821 vacuolization, pyknotic nuclei, medullary congestion, and moderate to severe necrosis. Treatment with dexmedetomidine shows normal glomeruli and slight edema of the tubular cells. These findings provide the first evidence that dexmedetomidine can reduce the renal injury caused by I-R of the kidney, and may be useful in enhancing the tolerance of the kidney against renal injury.”
“Recurrent pelvic organ prolapse occurs PD173074 supplier rarely after obliterative procedures. The optimal surgical approach for therapy is unknown. We describe a case of recurrent prolapse after LeFort colpocleisis. The patient presented Prexasertib datasheet with stage III prolapse through the lateral vaginal channel. At surgery, the prolapse was repaired using a modified repeat colpocleisis and repeat perineorrhaphy. Transvaginal revision via modified repeat colpocleisis should be considered for treatment of recurrent pelvic organ prolapse after LeFort colpocleisis.”
“Background: US children consume folic acid from multiple sources. These sources may contribute differently to usual intakes above the age-specific tolerable upper intake level (UL) for folic acid and to folate and vitamin B-12 status.

Objective: We estimated usual daily folic acid intakes

above the UL and adjusted serum and red blood cell folate, serum vitamin B-12, homocysteine, and methylmalonic acid (MMA) concentrations in US children by age group and by the following 3 major folic acid intake sources: enriched cereal-grain products (ECGP), ready-to-eat cereals (RTE), and supplements containing folic acid (SUP).

Design: We analyzed data in 4 groups of children aged 1-3, 4-8, 9-13, and 14-18 y from the National Health and Nutrition Examination Survey (NHANES), 2003-2006 (n = 7161).

Results: A total of 19-48% of children consumed folic acid from ECGP only. Intakes above the UL varied from 0-0.1% of children who consumed ECGP only to 15-78% of children who consumed ECGP+RTE+SUP. In children aged 1-8 y, 99-100% of those who consumed >= 200 mu g folic acid/d from supplements exceeded their UL. Although <0.

Conclusions: The Brief Quality of Life Appraisal Profile was associated with measures of motivation, goal content

and progress, as well as relationships with demographic and standard quality of life measures. This measure identifies novel concerns and issues in treating patients with bladder cancer, necessary for a more comprehensive evaluations of their health-related quality of life.”
“Background: In vitro and animal studies have suggested that soy protein and isoflavones have favorable effects on glucose and insulin regulation, but intervention studies in humans are limited, and the results are controversial.

Objective: We investigated whether soy protein with isoflavones and soy isoflavone extracts could improve glycemic control and insulin sensitivity in postmenopausal women with early hyperglycemia.

Design: This was a randomized, double-blind, placebo-controlled trial that included 180 postmenopausal Hong Kong AZD8186 mw Chinese women with prediabetes or early untreated

diabetes. After a 2-wk adaptation period, participants were randomly assigned to 1 of 3 arms to receive 15 g soy protein and 100 mg isoflavones, 15 g milk protein and 100 mg isoflavones, or 15 g milk protein on a daily basis for 6 mo.

Results: Three-or 6-mo treatments with soy protein with or without isoflavone supplementation did not result in favorable changes JQEZ5 molecular weight in the descriptors for glycemic control and insulin resistance, namely fasting and 2-h postload glucose, fasting and postload insulin, glycated serum protein, and homeostasis model assessment for insulin resistance and beta-cell function.

Conclusions: This 6-mo randomized controlled trial did not support

the hypothesis that soy protein with or without isoflavone supplementation had favorable effects on glycemic control and insulin sensitivity among postmenopausal Chinese women. The favorable change in postload glucose needs to be further confirmed. Am J Clin Nutr 2010;91:1394-401.”
“BACKGROUND: Owing to persisting donor shortages, the use of “”marginal hearts”" this website has increased. Because patients who receive a marginal heart may require hemodynamic support in the early post-operative period, extracorporeal membrane oxygenation (ECMO) may be used until recovery of acute graft dysfunction.

METHODS: A retrospective file review of 124 primary adult heart transplant patients from 2003 to 2008 was conducted. We compared 17 patients who received post-transplant ECMO support with 107 transplant recipients without ECMO. Donor and recipient pre-transplant, intra-operative, and post-transplant clinical variables to 6 months after transplant were compared.

RESULTS: Pre-operative demographics of the 2 groups were similar. Eight (47%) of the patients in the ECMO group received marginal donor hearts, compared with 1 (1%) in the non-ECMO group (p < 0.05).

The aim of this study was to evaluate the predictive value and prognostic significance of angiogenesis in human non muscle invasive bladder cancer (NMIBC) treated by BCG immunotherapy. The frozen sections of 28

non muscle invasive bladder cancer specimens were stained with CD34 antibody to label the vascular endothelium using the standard streptavidinbiotin immunoperoxidase method. Angiogenic activity was measured using microvessel count determined by the expression of vascular markers CD34. The prognostic significance of tumor stage, grade, loci number, tumor size, age and CD34 expression in determining the risk for recurrence was studied with both univariate and multivariate methods C59 of analysis. According to univariate analysis of the prognostic significance for tumor stage, grade, tumor size, loci number, age and CD34 expression, in patients with NMIBC, the pT1 stage and high grade seem to be associated in a

statistically significant manner with higher risk for recurrence (P=0.004, P=0.004, respectively). In the other hand, multivariate Cox regression’s analysis showed that microvessel density and multiplicity were independent predictor of recurrence after BCG immunotherapy (p=0.016, p=0.032, respectively). This study provides strong YH25448 supplier evidence that CD34 MVD is associated with recurrence after BCG immunotherapy. Independent studies, however, will be required on larger cohort to validate these findings.”
“The aim of this study was to examine the effect of low-level laser therapy (LLLT) on the cell viability and the expression of hypoxia-inducible factor-1s (HIF-1s), bone morphogenic

protein-2 (BMP-2), osteocalcin, type I collagen, transforming growth factor-beta 1 (TGF-beta 1), and Akt in hypoxic-cultured human osteoblasts. Human fetal osteoblast cells (cell line 1.19) were cultured under 1 % oxygen tension for 72 h. Cell cultures were divided into two groups. At the experimental side, low-level laser (808 nm, GaAlAs diode) was applied at 0, 24, and 48 h. After irradiation, each cell culture was incubated 24 h more under hypoxia. Total energy was 1.2, 2.4, and 3.6 J/cm(2), respectively. Non-irradiated cultures served as controls. Comparisons between the two groups were analyzed by t test; a p value < 0.05 AP26113 mouse was considered statistically significant. Hypoxia resulted in a decrease in the expression of type I collagen, osteocalcin, and TGF-beta 1 (p < 0.001, p < 0.001, and p < 0.01, respectively). Cell viability and BMP-2 expression were not decreased by hypoxic condition. On the other hand, LLLT on hypoxic-cultured osteoblast promoted the expression of BMP-2, osteocalcin, and TGF-beta 1 (p < 0.05, p < 0.01, and p < 0.001, respectively). Cell proliferation was also increased time-dependently. However, hypoxia decreased in type I collagen expression (p < 0.001), and LLLT did not affect type I collagen expression in hypoxic-cultured osteoblasts.

The NSHD recruited participants at birth in 1946 and has followed them at regular intervals since then, whereas the MWS recruited women in middle age. For 541 women who were participants in both studies, we used statistical measures of association

and agreement to compare self-reported MWS data on body size throughout life and reproductive history, obtained in middle age, to NSHD data measured or reported close to the relevant ages. Likely attenuation of estimates of linear disease-exposure associations due to the combined effects of random and systematic errors was quantified using regression dilution ratios (RDRs).

Results: Data from the two studies were very strongly correlated for current height, weight and body mass index, and age at menopause (Pearson r = 0.91-0.95), strongly correlated Compound Library for birth weight, parental heights, current waist and hip circumferences and waist-to-height ratio (r = 0.67-0.80), and moderately correlated for age at menarche and waist-to-hip ratio (r = 0.52-0.57).

Self-reported categorical body size and clothes size data for various ages were moderately to strongly associated with anthropometry collected at the relevant times (Spearman correlations 0.51-0.79). Overall agreement between the studies was also good for most quantitative variables, although all exhibited both random and systematic Kinase Inhibitor Library purchase reporting error. RDRs ranged from 0.66 to 0.86 for most variables (slight to moderate attenuation), except weight and body mass index (1.02 and 1.04, respectively; little or no attenuation), and age at menarche, birth weight and waist-to-hip ratio (0.44, 0.59 and 0.50, respectively; substantial attenuation).

Conclusions: This study provides

some evidence that self-reported data on certain anthropometric and reproductive factors may be adequate for describing disease-exposure associations in large epidemiological studies, provided that the effects of reporting errors are quantified and the results are interpreted with caution.”
“Objective: Evaluation of 3 different kinds of buy KU-55933 autologous substitutes for simple myringoplasty.

Study Design: Retrospective review of myringoplasty cases.

Patients: A total of 117 patients (52 women with 52 ears and 65 men with 65 ears) with an average age of 25.6 years (range, 12-51 yr) were examined. Forty-two cases exhibited large perforations, and 75 exhibited small perforations.

Intervention: Myringoplasty with temporal fascia, tragus perichondrium, or tragus cartilage-perichondrium composite grafts were randomly used in this comparative study. All the 117 operations were performed by a single surgeon.

Main Outcome Measures: Otoscopic findings as assessed by a hearing examination using a quad-frequency pure-tone average air-bone gap.

Results: Recurrent defects were not observed in the small perforation group repaired with autologous substitutes. The graft acceptance rate in this group was 100%.

Primary outcome was treatment success of aztreonam monotherapy. Secondary analyses included need for modification to antimicrobial therapy, patients transitioned to aztreonam from another empiric regimen, and patients receiving aztreonam in combination with other antibacterial agents.

ResultsIn patients prescribed aztreonam for first fever, 11 of 27 (40.7%) patients who received aztreonam alone and 19 of 40 (47.5%) given

aztreonam plus another antibiotic responded within 96h (P=0.62). Twenty-four (89%) www.selleckchem.com/products/oligomycin-a.html patients prescribed aztreonam monotherapy were alive when FN resolved or treatment ended. Infectious mortality was low (1 patient, 3.7%). In patients prescribed aztreonam monotherapy following an adverse reaction to cefepime, 6 of 11 (54.5%) responded within 96h of initiating aztreonam; 10 (91%) were alive when FN resolved or treatment ended.

ConclusionAztreonam monotherapy find more may be acceptable for use in patients with a history of beta-lactam hypersensitivity or following an adverse reaction with another beta-lactam. Further

studies are needed to compare efficacy of aztreonam monotherapy with other therapies for the treatment of FN.”
“SETTING: Two towns in Campo de Gibraltar, southern Spain, with a small foreign population and higher tuberculosis (TB) incidence and human immunodeficiency virus (HIV) prevalence than the national average.

OBJECTIVE: To determine the relationship between HIV-TB and P005091 Ubiquitin inhibitor non-HIV-TB incidence

and social deprivation and other potential individual and contextual determinants.

METHODS: In a cross-sectional longitudinal study, individual TB case variables were identified from three sources-routine surveillance, laboratory and hospital discharge records-from 1997 to 2007. Community variables were obtained at the census tract level. A deprivation index was calculated based on percentages of unemployment, low educational level and unskilled labour. Multilevel Poisson models were estimated for TB incidence rates for patients with and without HIV.

RESULTS: A total of 490 TB cases were included. Sex and age at individual level and deprivation and residence in the port area at census tract level were associated both with HIV-related TB and with non-HIV-TB. Household crowding contextual variables were also associated with HIV-related TB incidence. Full models account for 78.9% and 51.7% reductions in second-level variance.

CONCLUSION: Socio-economic deprivation is associated with higher rates of HIV-TB and non-HIV-TB. Diverse individual and contextual potential risk factors suggest different pathways of transmission. It is necessary to extend the framework for intervention beyond individual-based strategies to the socio-economic contexts in which people live.”
“We identified 22 cases of influenza infection among renal transplant recipients and matched them with 66 controls by influenza season to explore risk factors for influenza infection.

05, chi (2)). This systematic review confirms that OS-MRS stratifies the mortality risk in the three-risk classification subgroups of patients. The OS-MRS can be used for pre-operative identification of high-risk patients undergoing primary Roux-en-Y gastric bypass surgery.”
“A 55-year-old man with scleroderma treated with prednisone and etanercept presented with enlarging sporotrichoid nodules on

the forearm. Microscopically, there were large circumscribed dermal and subcutaneous nodules of spindled and epithelioid cells, resembling a spindle cell neoplasm. Small foci of neutrophils were also present, and a subsequent Ziehl-Neelsen stain highlighted beaded acid-fast bacilli in the interstitium. Tissue culture demonstrated Mycobacterium

chelonae. Cutaneous mycobacterial spindle Blebbistatin datasheet cell pseudotumor is an exceedingly rare lesion, with only 6 previously reported cases. Although these included patients with autoimmune disease receiving immunosuppressive therapy, this is the first case reported in association with a tumor necrosis factor alpha inhibitor, etanercept. Furthermore, this represents the first mycobacterial spindle cell pseudotumor described in association with M. chelonae. Mycobacterial spindle cell pseudotumor should be considered in the differential diagnosis of cutaneous spindle cell proliferations, especially in immunocompromised patients.”
“A 72-year-old man with diabetes mellitus and hypertension was admitted to our hospital with lightheadedness. The patient showed lateropulsion to the right side, but his neurological findings were otherwise normal. Brain magnetic resonance AR-13324 cost images SB273005 showed a fresh ischemic infarct in the left dorsal

part of the lower pons. Body lateropulsion is characterized by an irresistible falling to one side and has been reported in lesions in several brain regions. However, it has rarely been reported in pontine lesions. We suggest that physicians should be aware that pontine lesions can cause isolated body lateropulsion without other neurological deficits.”
“OBJECTIVES: Glycogen synthase kinase-3 beta (GSK-3 beta)/beta-catenin signaling mediates osteogenesis in response to mechanical loading. We tested the hypothesis that local administration of a GSK-3 beta inhibitor could stimulate new bone formation in the expanding premaxillary suture.

Materials and methods: Thirty-five SpragueDawley rats were subjected to premaxillary suture expansion using a helix spring. The experimental rats were given one or two local injections of SB-415286, a small-molecule GSK-3 beta inhibitor. Animals were administered calcein and sacrificed on day 7 to quantify new bone formation. To evaluate the proliferation and differentiation of osteoblasts, rats were labeled with bromodeoxyuridine on day 1 and sacrificed on day 2 or 4. beta-catenin expression was evaluated by immunohistochemical staining.

The mean treatment efficacies for the right and left sides using the FWCS were -1.85 +/- 0.82 and -1.70 +/- 0.71, respectively. Nine of 10 participants were satisfied with the procedure. Transient hyperpigmentation and slight exfoliation were observed in one patient after the last treatment, but this disappeared within 10 weeks.

CONCLUSION In eFT-508 treating

periorbital wrinkles, a 2,790-nm YSGG laser treatment might be an effective treatment modality with minimal complications.”
“Volatile organic compounds of Schenella pityophilus have been identified via solid-phase microextraction-gas chromatographymass spectrometry analysis. Ten compounds have been identified, in which 3-methylthio-1-propene was the most significant component. Some other components were previously identified

in Tuber aestivum and Tuber melanosporum.”
“BACKGROUND AND OBJECTIVE The water content of epidermis below the stratum corneum is more than 70%. The 2,940-nm wavelength is at the peak of water absorption, making it an ideal wavelength for ablation of skin. The purpose of this study was to determine the effectiveness and safety of a novel erbium-doped yttrium aluminum garnet (Er:YAG) laser with micron tips in the removal of cutaneous lesions.

METHODS GKT137831 datasheet Fourteen subjects with various cutaneous lesions received a single treatment with an Er:YAG laser, using an average fluence of 104.7 J/cm(2) (range 99-314 J/cm(2)), a mean repetition rate of 11.7 Hz, and straight and curved tips with a 400- to 600-mu m spot size. One subject received two treatments with a 1-month interval. The majority of subjects (80%, n = 12) did not require anesthesia.

RESULTS Clearance of 76% to 100% was obtained in 33% (n = 5) of subjects 1 month after treatment, 67% (n = 10) of subjects at 3 months, and 100% (n = 15) of subjects at 6 months. Investigators noted complete lesion clearance in all subjects 6 months after treatment. Ninety-three percent of subjects (n = 14)

reported satisfaction Selleckchem Duvelisib with the procedure and its outcome.

CONCLUSION The 2,940-nm wavelength combined with small micron spot size tips provides safe and effective clearance of cutaneous lesions, even in hard-to-reach locations.”
“Essential oil extracted from aerial parts of Artemisia nilagirica was analysed by gas chromatographymass spectroscopy. Forty-three constituents amounting to 98.16% of the total essential oil contents were identified. The essential oil contained approximately 79.91% monoterpenoids and 18.25% sesquiterpenoids. a-Thujone (36.35%), beta-thujone (9.37%), germacrene D (6.32%), 4-terpineol (6.31%), beta-caryophyllene (5.43%), camphene (5.47%) and borneol (4.12%) were identified as the major constituents. The essential oil exhibited significant antifungal activity against Rhizoctonia solani (ED50, 85.75?mg?L-1), Sclerotium rolfsii (ED50, 87.

In Europe both the amplitude and the magnitude of outbreaks of HFRS have increased. The mechanisms that drive the incidences are complex and multi-factorial and only partially due to increased awareness and improved diagnostic tools. Risk determinants include reservoir ecology, virus ecology and anthropogenic factors. The dogma of one specific rodent species as primordial reservoir for a specific hantavirus is increasingly challenged. New hantaviruses have been discovered in shrews, moles and bats and

increasing evidence points at host-switching events and co-circulation in multiple, sympatric reservoir species, challenging Selleck Vorinostat the strict rodent-virus co-evolution theory. Changing landscape attributes and climatic parameters determine fluctuations in hantavirus epidemiology, for instance through increased food availability,

prolonged virus survival and decreased biodiversity.”
“OBJECTIVE: To determine the utility of pulse pressure variation (Delta RESPPP) in predicting fluid responsiveness Bcl-xL protein in patients ventilated with low tidal volumes (V-T) and to investigate whether a lower Delta RESPPP cut-off value should be used when patients are ventilated with low tidal volumes.

METHOD: This cross-sectional observational study included 37 critically ill patients with acute circulatory failure who required fluid challenge. The patients were sedated and mechanically ventilated with a

V-T of 6-7 ml/kg ideal body weight, which was monitored with a pulmonary artery catheter and an arterial line. The mechanical ventilation and hemodynamic parameters, including Delta RESPPP, were measured before and after fluid challenge with 1,000 ml crystalloids or 500 ml colloids. Fluid responsiveness was defined as an increase in the cardiac index of at least 15%. ClinicalTrial.gov: NCT01569308.

RESULTS: A total of 17 patients were classified as responders. Analysis of the area under the ROC curve (AUC) showed that the optimal cut-off point for Delta RESPPP to predict fluid responsiveness was 10% (AUC = 0.74). Adjustment of the Delta RESPPP to account for driving pressure did not improve the accuracy (AUC = 0.76). A Delta RESPPP >= 10% was a better predictor of fluid TGF-beta inhibitor responsiveness than central venous pressure (AUC = 0.57) or pulmonary wedge pressure (AUC = 051). Of the 37 patients, 25 were in septic shock. The AUC for Delta RESPPP >= 10% to predict responsiveness in patients with septic shock was 0.84 (sensitivity, 78%; specificity, 93%).

CONCLUSION: The parameter Delta RESPPP has limited value in predicting fluid responsiveness in patients who are ventilated with low tidal volumes, but a Delta RESPPP. 10% is a significant improvement over static parameters. A Delta RESPPP >= 10% may be particularly useful for identifying responders in patients with septic shock.