jejuni were used for this analysis, the human clinical isolate 11168 and the chicken isolate 331. Free glycan (H-disaccharide, A-blood group antigen and α1-2 mannobiose) were added to the media at a final concentration of 100 μM just prior to addition of the bacteria. Acknowledgements This work was partially funded by and CJD and LHT are supported by a Queensland State Government, Department of Science, Information AZD1480 concentration Technology, Innovation and the Arts Research Partnerships Program. GT is supported by a Griffith University Postgradute Research Scholarship. Electronic supplementary material Additional file 1: Table of Glycans. (DOC 132 KB) References www.selleckchem.com/products/gsk2126458.html 1. Smith DC, Lord JM, Roberts

LM, Johannes L: Glycosphingolipids as toxin receptors. Semin Cell Dev Biol 2004,15(4):397–408.PubMedCrossRef 2. Lehmann F, Tiralongo E, Tiralongo J: Sialic acid-specific lectins: occurrence, specificity and function. Cell Mol Compound C Life Sci 2006,63(12):1331–1354.PubMedCrossRef 3. Day CJ, Tiralongo J, Hartnell RD, Logue CA, Wilson JC, von Itzstein M, Korolik V: Differential carbohydrate recognition by Campylobacter jejuni strain 11168: influences of temperature and growth conditions. PLoS One 2009,4(3):e4927.PubMedCrossRef 4. Day CJ, Semchenko EA, Korolik V: Glycoconjugates play a key role in campylobacter jejuni infection: interactions between host and pathogen. Front Cell Infect Microbiol 2012, 2:9.PubMedCrossRef 5. Newburg DS, Ruiz-Palacios GM, Morrow AL: Human milk DOK2 glycans protect

infants against enteric pathogens. Annu Rev Nutr 2005, 25:37–58.PubMedCrossRef 6. Morrow AL, Ruiz-Palacios GM, Jiang X, Newburg DS: Human-milk glycans that inhibit pathogen binding protect breast-feeding infants against infectious diarrhea. J Nutr 2005,135(5):1304–1307.PubMed 7. Yamaoka Y: Roles of Helicobacter pylori BabA in gastroduodenal pathogenesis. World J Gastroenterol 2008,14(27):4265–4272.PubMedCrossRef 8. Juge N: Microbial adhesins to gastrointestinal mucus.

Trends Microbiol 2012,20(1):30–39.PubMedCrossRef 9. Mahdavi J, Sonden B, Hurtig M, Olfat FO, Forsberg L, Roche N, Angstrom J, Larsson T, Teneberg S, Karlsson KA, et al.: Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation. Science 2002,297(5581):573–578.PubMedCrossRef 10. McAuley JL, Linden SK, Png CW, King RM, Pennington HL, Gendler SJ, Florin TH, Hill GR, Korolik V, McGuckin MA: MUC1 cell surface mucin is a critical element of the mucosal barrier to infection. J Clin Invest 2007,117(8):2313–2324.PubMedCrossRef 11. Varki A: Multiple changes in sialic acid biology during human evolution. Glycoconj J 2009,26(3):231–245.PubMedCrossRef 12. Le Pendu J: Histo-blood group antigen and human milk oligosaccharides: genetic polymorphism and risk of infectious diseases. Adv Exp Med Biol 2004, 554:135–143.PubMedCrossRef 13. Suzuki N, Laskowski M Jr, Lee YC: Phylogenetic expression of Galalpha1–4Gal on avian glycoproteins: glycan differentiation inscribed in the early history of modern birds.