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nationwide inpatient sample database. Arch Surg 2012, 147:607–612.PubMedCrossRef Competing interest The authors declare that they have no competing interest. Authors’ contribution RB and DF was involved in the clinical management of the patient. AL and RL contributed conceiving the manuscript. RB, DF and AL performed the operation. RL and RB wrote the manuscript. AL and DF reviewed the literature. All authors read and approved the manuscript. MP and RB answer to the reviewer and all the authors approved the corrections.”
“Background Portal vein aneurysm (PVA) is defined as a focal dilatation of the portal venous system, greater than Ketotifen 2 cm [1]. PVA is a rare vascular anomaly, observed in 0.43% [2] but its incidence was increasing

in recent years with the enlarged use of magnetic resonance (MR) and computed tomography (CT) [3]. Most common sites are the main portal vein and confluence of splenic and superior mesenteric veins, forming extra-hepatic portal vein aneurysm (EPVA). Although risk factors like portal hypertension and liver cirrhosis have been highlighted, the etiology remains to be clarified. PVA may be associated with various complications: thrombosis, aneurismal rupture, inferior vena cava obstruction and duodenal compression. Thrombosis is the most frequent complication with complete thrombosis and non-occlusive thrombus occurring in 13.6% and 6%, respectively [3]. Herein we report the case of a giant EPVA with complete thrombosis, among the largest described so far. A conservative treatment showed satisfying clinical and radiological response. We reviewed the English literature, disclosing 13 cases of thrombosed EPVA in order to assess current treatment [4–13].