Patients with total humeral reconstruction had worse scores than those with distal humeral reconstruction. Twenty-four patients died of disease at a mean of thirteen months after surgery. Local tumor control was achieved in all patients. In the revision group, the mean Inglis-Pellicci score was 76 points. The Inglis-Pellicci score was significantly better for selleck products patients in the tumor group. Eight patients (15%) had a deep periprosthetic infection, requiring amputation in one patient (2%) and prosthetic

removal in two patients (4%). Four patients (8%) had the implants revised for aseptic loosening.

Conclusions: Modular prostheses of the distal end of the humerus provide a stable reconstruction of the elbow with satisfactory function GW786034 and disease control in patients with a tumor, but careful patient

selection is required when the prostheses are used for revision surgery in patients without a tumor.”
“A systematic investigation of structural and magnetic properties of FePt/FeRh bilayers has been carried out. The transition temperature of single FeRh layer is higher than that of FePt/FeRh bilayer. A sharp decrease in coercivity is observed at transition temperature for FePt/FeRh bilayer. The thickness FePt dependence of exchange bias field and unidirectional anisotropy constant are discussed. Of interest is the exchange bias effect that appears in FePt/FeRh bilayer and the unidirectional anisotropy constant, which is very large (up to 0.8 erg/cm(2)), suggesting that this system can be applied for spin-valve sensors and heat assisted magnetic recording medium. It may also provide some useful information for better understanding of the mechanism of exchange bias. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3062813]“
“To study the effects of Pseudostellaria heterophylla (Miq.) Pax (TZS) on CYP450

Dihydrotestosterone inhibitor activities in rats, six probe drugs (phenacetin, tolbutamide, metoprolol, midazolam, omeprazole, and bupropion) were simultaneously given to rats which were randomly divided into 2 groups (n = 7 each): Control-group and TZS-group. In TSZ-group, rats were given 5 g/kg . d TSZ orally. Plasma concentrations of six probes were measured by LC-MS after administration for 14 consecutive days. Pharmacokinetic parameters were calculated by DAS 2.0 program. The result showed there was no obvious difference in pharmacokinetic parameters for phenacetin, metoprolol, midazolam, omeprazole and bupropion, except tolbutamide. The MRT(0.t), MRT(0-infinity) and t(1/2) of tolbutamide in TZS-group were 5.696 +/- 0382, 5.810 +/- 0.503, and 330 +/- 1.16 h, where in control-group were 9.142 +/- 0.465, 9.497 +/- 0574, and 5.06 +/- 0.67 h, they were all shorten significantly (P < 0.01). In conclusion, TZS can induce the activity of CYP2C11 of rats significantly after intragastric administration for 14 days.