Kim et al. demonstrated that that the sigmoid colon received the highest mean D2 when compared to the rectum and small bowel [28]. Their study

revealed that with the prescribed dose of 600 cGy, the sigmoid colon received the highest mean D2 (408 cGy) followed by the small bowel (379 cGy), and rectum (373 cGy). In our study, we clearly demonstrated that the small bowel D2 was higher than the sigmoid colon D2 (6.8 Gy and 6.5 Gy, respectively). We also found that the sigmoid colon D2 and D5 values were significantly higher with larger CTVs (Table 4). The small bowel D2 values were higher in group 2 than in group 1, and this difference was almost statistically CHIR98014 price significant (P = 0.07). The results of our study demonstrate that CT-guided BRT this website planning is superior to conventional point A planning in terms of both conformity of target coverage and evaluation of OARs, including the sigmoid colon, bowel, bladder, and rectum. Although this superiority was clear for small CTVs, for large CTVs both the conventional and CTV plans had the drawbacks of inadequate target coverage and/or excessive radiation doses to normal organs. To ascertain the potential benefit of treatment outcomes, such as tumor control probability and morbidity, ICR with image-guided 3D planning will be pursued and correlated with the

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