Figure 1 X-ray of chest on day of injury. Black arrows: subcutaneous emphysema. White arrows: pneumomediastinum An emergency operation was indicated for stabilization of the unstable lumbar vertebral fracture and the patient was observed postoperatively at the Intensive Care Unit

(ICU). In this phase the Ear/Nose/Throat specialist (ENT) was consulted and during examination the patient only complained of dysphagia and painful coughing. Subsequently, a flexible laryngoscopy was performed which revealed a lesion in the upper esophagus just under the level of the upper esophageal sphincter. Inhibitors,research,lifescience,medical A contrast-swallow examination showed contained leaking of contrast from the posterior wall Inhibitors,research,lifescience,medical of the cervical esophagus into the retropharyngeal area next to the esophagus (Figure ​(Figure22). Figure 2 Contrast swallow examination on day of injury. Black arrows: contained leakage (contrast extravasation). White arrows: contrast descending in esophagus Based on these findings Inhibitors,research,lifescience,medical and the patient’s clinically stable condition conservative treatment was initiated consisting of nutrition via a nasogastric tube. A control

contrast-swallow video examination on the tenth day after Volasertib solubility trauma showed minimal contrast extravasation into a blind sinus (Figure ​(Figure3).3). An episode of fever and increased infectious laboratory parameters (leukocyte count 15,1 × 109/L and selleck chem C-reactive protein 17 mg/L) however were reason to restart antibiotics (Amoxicillin) Inhibitors,research,lifescience,medical intravenously on the 13th day. The following day the patient also coughed up some purulent fluid and had painful swelling on the left side of the neck, suspicious for an abscess. Laryngoscopy was performed 2.5 weeks after Inhibitors,research,lifescience,medical the trauma and showed no abnormalities. X-ray of the cervical spine showed minimal subcutaneous emphysema. Normal diet was gradually resumed and the nasogastric tube was removed. After 3 weeks the patient was discharged. ENT follow-up showed no evidence for continued leakage. Figure 3 Contrast swallow video examination on day 10. Black arrows: contrast leakage (extravasation)

in blind sinus. White arrows: contrast continuing in esophagus. AV-951 White dotted arrows: nasogastric tube. Written informed consent was obtained from this patient. Conclusions Cervical esophageal rupture due to blunt trauma without associated injuries is very rare. Esophageal rupture is associated with high mortality and morbidity; early diagnosis and subsequent treatment can add to a beneficial outcome[2,5]. We present a unique report of a case of a high cervical esophageal rupture after a fall from height without associated injuries in the cervical area. Case reports about traumatic esophageal ruptures are not new; however, almost all cases describe motor vehicle accidents [6-15].