Despite the laws regulating the use of helmets, safety equipment and the practice of traffic PLX3397 datasheet safety most of these rules are blatantly ignored in Brazil by motorcycle drivers. The cause of death described as drowning is also described as an important cause of death in literature [11, 15]. In this series there was a large number of drowning incidents among 1-4 year olds, and another peak among 10-17 year olds.

The deaths in the younger age group may be due to negligence or absence of P005091 ic50 preventive measures such as grids or screens around pools. In a study from India evaluating deaths in children under 5 years, drowning was the first cause. In the 10-17 age group, these deaths are more common in boys, usually engaged in work activities or recreation near ponds or rivers [15]. Another study conducted in China indicates that the majority of these accidents occur in rural areas [13]. Approximately 50% of deaths in this study occurred at accident scenes, and most of them were due to gunshot wounds. These data are consistent with a study conducted in another region in the state of São Paulo and in several CAL-101 molecular weight American cities such as Los Angeles, San Francisco and Vermont [24, 25].

In another American series, in Colorado, we found that most deaths occurring in less than 24 hours were due to traffic accidents [26]. Regarding intent, this study showed that the primary cause of death was homicide (50.6%), followed by accident (48.5%) and much lower, suicide (0.9%). These data are extremely alarming when considering the growing violence in our society and the social and economic repercussions that this may cause. The same pattern of intent was described in a study conducted in Recife, in the state of Pernambuco, and in another U.S. study conducted in Denver [6, 27]. Other studies in Canada, Nepal, South Africa and China show accidents as the leading cause of death in children and adolescents [10, 13, 28, 29]. It is interesting to note that a study in India, relating to the period of 1994 to 2005, showed that there were no cases of homicide in adolescents under 19 years of age [12]. In relation to suicide,

this is an emerging problem in developed countries. In the U.S.A., it is the second most common cause of death in children in the 10-14 year age group and in a study conducted in Sweden L-NAME HCl in 2002, it was the first cause of death among 5-25 year olds [9, 12]. Undisputed is the association between violence and alcohol misuse, illicit drug use and availability of firearms [4]. Other factors also related to homicide in younger children were described by Fujiwara et al. [30] in a study conducted in 2009, which used data from the National Violent Injury Statistics System in the U.S.A. The study indicated that the main victims of homicide aged less than 2 years were boys, whose parents had depression and financial problems [30]. The first measure in reducing deaths from trauma-related causes is prevention.