This paper uses anesthesia and intensive care (AIC) in France as a case research in how to report this baseline. Approach An IRB-approved, online anonymous closed survey was posted to AIC residency program administrators and AIC simulation program directors in France from January to February 2021. The researcher-developed review contained 65 concerns across five areas facilities’ qualities, curricular attributes, programs’ characteristics, instructors’ characteristics, and simulation perceptions and views. Conclusions The participation rate was 31/31 (100%) withon a decentralized approach by which specific organizations or local consortia conduct simulation for a discipline in a relatively homogeneous way, recommending the feasibility for nationwide directions. This approach provides useful clues for AIC as well as other disciplines to develop an extensive and meaningful program matching existing objectives and shutting the identified spaces. The serum IGF-1/IGFBP-3 proportion features various prospective applications in development hormone-related conditions. This study aimed to investigate the performance of this IGF-1/IGFBP-3 ratio, independently plus in combo with serum IGF-1 and IGFBP-3, in the diagnosis of growth hormone deficiency (GHD) in kids with brief stature (SS). A 7-year cross-sectional observational research had been performed on 235 kiddies with SS. Participants with known disorders which might affect IGF-1 apart from GHD had been omitted. Individuals were classified into GHD (letter = 64) and non-GHD (n = 171) teams. GHD had been understood to be a slow development price (< 25th percentile over twelve months) and suboptimal human growth hormone (GH) reaction to two GH stimulation tests (peak biocontrol bacteria GH < 6.25 ng/mL making use of the DiaSorin Liaison assay). The susceptibility and specificity of serum IGF-1, IGFBP-3 and IGF-1/IGFBP-3 molar ratio, separately and in various combinations, were determined. GHD ended up being diagnosed in 27.2% of participants. Among all studied factors, a low serum IGF-1/IGFBP-3 ratio demonstrated the best sensitiveness for GHD (87.5%), with a comparable specificity (83.0%). The combination of low serum IGF-1, IGFBP-3 and IGF-1/IGFBP-3 ratio demonstrated the greatest specificity for GHD (97.7%), whereas the blend of normal serum IGF-1, IGFBP-3, and IGF-1/IGFBP-3 ratio demonstrated the best specificity for a non-GHD reason for SS (100.0%).Our information claim that the serum IGF-1/IGFBP-3 ratio is a helpful marker when it comes to diagnosis of GHD in children who do n’t have other problems which will influence serum IGF-1 levels. Further huge scientific studies are expected to ensure the diagnostic energy associated with the serum IGF-1/IGFBP-3 ratio.Metachronous osteosarcomas (MOS) are currently defined as tumors that arise in a way and site strange for typical metastasis. In this specific article, we evaluated the present literature regarding the occurrence of metachronous osteosarcoma and introduced a case from our center. Our patient, a 10-year-old woman, offered metachronous osteoblastic osteosarcoma of this left distal femur ∼5 years following the successful treatment for osteosarcoma associated with right distal femur. Even after several relapses, full remission (CR) was accomplished following the first osteosarcoma and after the metachronous osteosarcoma. The literature study revealed that metachronous osteosarcoma takes place in 3.4 to 5.4% of osteosarcoma patients. Enough time interval involving the diagnosis associated with the preliminary osteosarcoma together with metachronous tumor ranged from 0.2 to 14.3 many years (median 2.5 y). MOS seems to have differences in localization and metastatic spread, in addition to an alternative success structure compared to major osteosarcoma and osteosarcoma recurrence. Survival (median 4.3 y, range 0 to 24.6 y) appears to be from the time-interval to diagnosis of MOS. In specific, early MOS ( less then 24 mo after primary analysis) seem to have a poorer prognosis. Therefore, the occurrence of MOS at oncological unusual web sites is highly recommended as a differential diagnosis in osteosarcoma survivors. The kangaroo mama attention (KMC) technique for preterm and low-birthweight (LBW) neonates, which contains skin-to-skin contact, is thought having a beneficial impact on medical results. Thus, the present meta-analysis aims to measure the impact of KMC on neonatal death and amount of hospitalization in contrast to mainstream treatment. an organized literature search of researches posted between 1988 and 2021 discovered 24 trials involving 19,980 individuals, of which 10,354 got KMC and 9626 were controls under mainstream older medical patients treatment. To measure the effect of applying KMC in preterm LBW neonates on mortality and the period of medical center stay, statistical analysis utilizing dichotomous and continuous evaluation practices had been performed employing fixed and random designs to determine odds ratios (ORs) with 95% self-confidence intervals (95% CIs). In comparison with the control group, the utilization of KMC in preterm LBW neonates triggered somewhat lower death but had no significant effect on the size of hospitalization. Even more studies are needed to verify current results.When comparing to the control group, the utilization of KMC in preterm LBW neonates triggered substantially reduced death but had no considerable impact on the length of hospitalization. Even more researches are expected learn more to confirm the existing conclusions.